发明名称 Fremgangsmåte for fremstilling av imidazol-forbindelser
摘要 A process for the preparation of 4-(3-chlorophenyl)-6-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl)methyl]-1-methyl-2(1H)-quinolinone which comprises reacting 6-(4-chlorobenzoyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone with a C6-8alkyllithium compound, 1-methylimidazole and a tri(C4-6alkyl)silyl halide to obtain better yields of the above product.
申请公布号 NO20034003(D0) 申请公布日期 2003.09.10
申请号 NO20030004003 申请日期 2003.09.10
申请人 JANSSEN PHARMACEUTICA NV 发明人 FILLIERS, WALTER FERDINAND MARIA;BROECKX, RUDY LAURENT MARIA;LEURS, STEFAN MARCEL HERMAN
分类号 A61K31/4709;A61P35/00;C07D401/06;C07D403/06;(IPC1-7):C07D 主分类号 A61K31/4709
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