发明名称 UREA AND URETHANE DERIVATIVES AS INTEGRIN INHIBITORS.
摘要 <p>Novel urea and urethane derivatives of general formula (I) in which R1, R2, R3, R5, R5', X, Y, B, m, n and o are as defined in Patent Claim 1 , and physiologically acceptable salts or solvates thereof are integrin inhibitors and can be employed for combating thromboses, cardiac infarction, coronary heart disease, arteriosclerosis, inflammation, tumors. Osteoporosis, infections and restenosis after angioplasty or in pathological processes maintained or propagated by antiogenesis.</p>
申请公布号 MXPA03005431(A) 申请公布日期 2003.09.10
申请号 MX2003PA05431 申请日期 2001.11.30
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 发明人 ALFRED JONCZYK
分类号 A61K31/4184;A61K31/44;A61K31/4402;A61P1/04;A61P7/02;A61P9/00;A61P9/04;A61P9/10;A61P9/14;A61P13/12;A61P17/02;A61P17/06;A61P19/02;A61P19/10;A61P25/28;A61P27/02;A61P27/06;A61P29/00;A61P31/00;A61P31/04;A61P31/10;A61P31/12;A61P35/00;A61P35/04;A61P41/00;A61P43/00;C07D213/74;C07D235/30;(IPC1-7):A61K31/44 主分类号 A61K31/4184
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