| 发明名称 |
Cells immortalized with telomerase reverse transcriptase for use in drug screening |
| 摘要 |
The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers.
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| 申请公布号 |
US6617110(B1) |
申请公布日期 |
2003.09.09 |
| 申请号 |
US20000721456 |
申请日期 |
2000.11.22 |
| 申请人 |
GERON CORPORATION;UNIVERSITY TECHNOLOGY CORPORATION |
发明人 |
CECH THOMAS R.;LINGNER JOACHIM;NAKAMURA TORU;CHAPMAN KAREN B.;MORIN GREGG B.;HARLEY CALVIN B.;ANDREWS WILLIAM H. |
| 分类号 |
A01K67/027;A61K31/70;A61K31/7088;A61K35/12;A61K38/00;A61K38/45;A61K38/55;A61K39/00;A61K39/395;A61K48/00;A61P35/00;A61P43/00;C07K5/10;C07K5/107;C07K5/117;C07K7/06;C07K7/08;C07K14/47;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/12;C12N15/09;C12N15/113;C12N15/12;C12N15/54;C12N15/85;C12P21/08;C12Q1/02;C12Q1/48;C12Q1/68;C12R1/19;C12R1/84;C12R1/91;G01N33/15;G01N33/48;G01N33/50;G01N33/53;G01N33/566;G01N33/573;(IPC1-7):C12G1/68;C12N5/00 |
主分类号 |
A01K67/027 |
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