| 发明名称 |
Human NK-3 related prostate specific gene-1 |
| 摘要 |
The present invention relates to a novel member of the NK family of homeobox genes. In particular, isolated nucleic acid molecules are provided encoding the human NK-3 prostate specific gene 1 (NKX3.1) protein. NKX3.1 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of NKX3.1 activity. Also provided are diagnostic methods for detecting prostate cancer and other cancers and therapeutic methods for prostate cancer and other cancers.
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| 申请公布号 |
US6617129(B2) |
申请公布日期 |
2003.09.09 |
| 申请号 |
US19980105470 |
申请日期 |
1998.06.26 |
| 申请人 |
HUMAN GENOME SCIENCES, INC. |
发明人 |
HE WEI-WU;CARTER KENNETH C. |
| 分类号 |
G01N33/50;A61K31/555;A61K31/711;A61K38/00;A61K41/00;A61K45/00;A61K48/00;A61N5/06;A61P13/08;A61P35/00;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;(IPC1-7):C12P21/06;C12N15/00;C12N15/63;C12N5/00;C07H21/04 |
主分类号 |
G01N33/50 |
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