发明名称 |
RATIONELT KONSTRUEREDE MEGANUKLEASER MED ÆNDRET SEKVENSSPECIFICITET OG DNA-BINDINGSAFFINITET |
摘要 |
Rationally-designed LAGLIDADG meganucleases and methods of making such meganucleases are provided. In addition, methods are provided for using the meganucleases to generate recombinant cells and organisms having a desired DNA sequence inserted into a limited number of loci within the genome, as well as methods of gene therapy, for treatment of pathogenic infections, and for in vitro applications in diagnostics and research. |
申请公布号 |
DK2628794(T3) |
申请公布日期 |
2016.08.15 |
申请号 |
DK20130164628T |
申请日期 |
2006.10.18 |
申请人 |
Precision Biosciences |
发明人 |
HELLINGA, Homme, W.;SMITH, James, Jefferson;JANTZ, Derek |
分类号 |
C12N9/22;C12N15/90 |
主分类号 |
C12N9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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