摘要 |
<p>A compound of formula (I) and pharmaceutically acceptable salts, solvates and hydrolysable esters thereof wherein: X<SUP>1 </SUP>is O or S; X<SUP>2 </SUP>is O or S; n is 1-3, One of Y and Z is N, and the other is O; R<SUP>1 </SUP>and R<SUP>2 </SUP>are independently halogen, H, CH<SUB>3</SUB>, OCH<SUB>3 </SUB>or C<SUB>1-3 </SUB>alkyl; Each R<SUP>3 </SUP>independently is halogen, CF<SUB>3</SUB>, C<SUB>1-6 </SUB>straight or branched alkyl; R<SUP>4 </SUP>and R<SUP>5 </SUP>are independently H or C<SUB>1-3 </SUB>alkyl. y is 0, 1, 2, 3, 4 or 5.</p> |