| 发明名称 |
Process For The Preparation Of Hyperpolarized Carboxylate Compounds |
| 摘要 |
The present invention relates to a process for the preparation of aqueous solutions of [1-13C]-hyperpolarized carboxylate containing molecules of diagnostic interest that comprises parahydrogenating with molecular parahydrogen unsaturated alkenyl or alkynyl esters of the concerned 13C-carboxylate molecules. |
| 申请公布号 |
US2016263256(A1) |
申请公布日期 |
2016.09.15 |
| 申请号 |
US201415031860 |
申请日期 |
2014.10.27 |
| 申请人 |
BRACCO IMAGING SPA |
发明人 |
AIME Silvio;BOI Tommaso;CERUTTI Erika;REINERI Francesca |
| 分类号 |
A61K51/04;C07C69/14;C07C51/09;C07C69/716;A61B5/055;C07C233/47;C07C69/68;B01J31/24;G01R33/56;C07C67/283;C07C231/12 |
主分类号 |
A61K51/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A Para-Hydrogen Induced Polarization process for a preparation of an [1-13C]-hyperpolarized carboxylate containing molecule comprising hydrogenating with molecular para-hydrogen an unsaturated C2-C4 alkenyl or alkynyl ester of said carboxylate containing molecule. |
| 地址 |
Milan IT |
