主权项 |
1. A method for inhibiting the activity of angiotensin-converting enzyme in a subject in need of such inhibition comprising administering to said subject an effective amount of a fish skin fermentation composition obtained by co-culturing a fish skin and Aspergillus in a medium and collecting the supernatant, wherein the fish skin is derived from yellowtail fish, bream, coho salmon, cavalla, turbot, Sebastes species, puffer, ray, tuna, eel, carp, rainbow trout, gold fish, native carp, crucian carp and/or Oreochromis species, and Aspergillus is selected from the group consisting of Aspergillus oryzae, Aspergillus niger and Aspergillus phoenicis. |