发明名称 PREPARATION AND USE OF FISH SKIN FERMENTATION LIQUID OBTAINED BY FERMENTING FISH SKIN WITH ASPERGILLUS
摘要 The present invention relates to a method for fermenting fish skin by using Aspergillus. Also provided is a use of the fermentation liquid obtained by fermenting fish skin with Aspergillus obtained from the method in inhibiting the activity of tyrosinase, inhibiting the activity of angiotensin-converting enzyme and/or improving the survival of fibroblasts.
申请公布号 US2016263165(A1) 申请公布日期 2016.09.15
申请号 US201615163005 申请日期 2016.05.24
申请人 FOOD INDUSTRY RESEARCH AND DEVELOPMENT INSTITUTE 发明人 HUANG SHU-CHEN;LIU PEI-JOU;LIAO CHIAO-MING;CHAN HING-YUEN
分类号 A61K35/60;C12N9/02;C12P1/02 主分类号 A61K35/60
代理机构 代理人
主权项 1. A method for inhibiting the activity of angiotensin-converting enzyme in a subject in need of such inhibition comprising administering to said subject an effective amount of a fish skin fermentation composition obtained by co-culturing a fish skin and Aspergillus in a medium and collecting the supernatant, wherein the fish skin is derived from yellowtail fish, bream, coho salmon, cavalla, turbot, Sebastes species, puffer, ray, tuna, eel, carp, rainbow trout, gold fish, native carp, crucian carp and/or Oreochromis species, and Aspergillus is selected from the group consisting of Aspergillus oryzae, Aspergillus niger and Aspergillus phoenicis.
地址 HSINCHU CITY TW