NOVEL TREATMENT OF NEURODEGENERATIVE DISEASES BY ALTERING LEVELS OF TRKB ISOFORMS AND/OR TRKC ISOFORMS
摘要
This invention relates to a method of treating or preventing neuro-degenerative disorders and neuro-developmental disorders by altering the ratio of the amount of full-length TrkB polypeptide to the amount of truncated TrkB polypeptides in a neuron or by altering the ratio of the amount of full-length TrkC polypeptide to the amount of truncated TrkC polypeptides in a neuron.
申请公布号
WO03071872(A1)
申请公布日期
2003.09.04
申请号
WO2002US16807
申请日期
2002.05.28
申请人
UNIVERSITY OF MARYLAND, BALTIMORE;KRUEGER, BRUCE, K.;KINGSBURY, TAMI, J.;BAMBRICK, LINDA, L.;DORSEY, SUSAN, G.
发明人
KRUEGER, BRUCE, K.;KINGSBURY, TAMI, J.;BAMBRICK, LINDA, L.;DORSEY, SUSAN, G.