| 摘要 |
Disclosed is a bonding method of a PMMA substrate for manufacturing a microfluidic device. According to an embodiment of the present invention, the bonding method of a PMMA substrate comprises the following steps of: a) arranging a first PMMA substrate having a microchannel, and a flat second PMMA substrate; b) modifying the surface of the first PMMA substrate to impart hydrophobicity to the microchannel, or selectively modifying the surface of the microchannel only; c) treating the surface of the first and second PMMA substrate with ethanol; and d) closely arranging the first and second PMMA substrates, and bonding the resultant product by heat pressing the same. The bonding method can bond a PMMA substrate at a relatively low temperature and pressure, and can manufacture a PMMA bonded substrate having excellent bond strength without altering a channel profile. |
