METHOD FOR PRODUCING ALCOHOLS FROM SUBSTRATES BY USING OXIDE REDUCTASES, TWO-PHASE SYSTEM COMPRISING AN AQUEOUS PHASE AND AN ORGANIC PHASE AND DEVICE FOR CARRYING OUT SAID METHOD

摘要

The invention relates to a method for producing alcohols from substrates by using oxide reductases, to a two-phase system comprising an aqueous phase and an organic phase and to a device for carrying out said method. The method for producing alcohols from substrates using oxide reductases is characterized by making an oxide reductase of microbial origin available in an aqueous solution and the substrate in an organic solution and by contacting the aqueous phase and the organic phase in a two-phase system. Surprisingly, said method leads to enzyme activities that last approximately 1000 hours. The inventive method allows the spatial decoupling of enzymatic reaction and cofactor regeneration, thereby increasing the effectivity of the reaction process.