Self-hardening calcium phosphate materials with high resistance to fracture, controlled strength histories and tailored macropore formation rates

摘要

A bone replacement material and therapy comprises the combination of calcium phosphate compounds and two or more soluble fillers in the form of fibers, mesh or other materials which have the dual functions of reinforcing an in vivo implant while dissolving at a programmed rate to form macropores capable of receiving natural bone ingrowth.