COMPOUNDS USEFUL IN THE TREATMENT OF ANTHRAX

摘要

This invention relates to a method of inhibiting growth of Bacillus anthracis, Bacillus cereus and/or Bacillus thuringiensis bacterial strains in a mammal comprising administration to a patient in need thereof a therapeutically effective amount of a carbapenem compound. In particular, this invention relates to a method of inhibiting growth of Bacillus anthracis, Bacillus cereus and/or Bacillus thuringiensis bacterial strains in a mammal using compounds having the structural formula (I) or a pharmaceutically acceptable salt, enantiomer, diastereomer or in vivo hydrolysable ester or mixture thereof. This invention further relates to the use of carbapenem compounds of formula I in the treatment of anthrax and other conditions which are related to an anthrax infection.