发明名称 |
Identification of free-B-ring flavonoids as potent COX-2 inhibitors |
摘要 |
The present invention provides a novel method for inhibiting the cyclooxygenase COX-2. The method is comprised of administering a composition containing a Free-enzyme B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids to a host in need thereof. The present also includes novel methods for the prevention and treatment of COX-2 mediated diseases and conditions. The method for preventing and treating COX-2 mediated diseases and conditions is comprised of administering to a host in need thereof an effective amount of a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids and a pharmaceutically acceptable carrier.
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申请公布号 |
US2003165588(A1) |
申请公布日期 |
2003.09.04 |
申请号 |
US20020091362 |
申请日期 |
2002.03.01 |
申请人 |
UNIGEN PHARMACEUTICALS, INC. |
发明人 |
JIA QI;NICHOLS TIMOTHY C.;RHODEN ERIC E.;WAITE SCOTT |
分类号 |
A61K31/352;A61K31/353;A61K31/7048;A61K36/00;A61K36/18;A61K36/28;A61K36/48;A61K36/53;A61K36/60;A61P29/00;A61P43/00;(IPC1-7):A61K35/78 |
主分类号 |
A61K31/352 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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