| 发明名称 |
Heterocyclic hydrazones for use as anti-cancer agents |
| 摘要 |
The invention relates to novel 2-benzimidazolyl-, 2-benzoxazolyl- and 2-benzothiazolyl hydrazones that are derived from 2-formylpyridine, 2-acylpyridines, acetyldiazines and acetyl(iso)quinolines. The invention also relates to a novel method for producing 2-benzimidazolyl-, 2-benzoxazolyl- and 2-benzothiazolyl hydrazones and to their use as useful anti-cancer therapeutic agents. The novel compounds are also active against multidrug-resistant cancer cells.
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| 申请公布号 |
US2003166658(A1) |
申请公布日期 |
2003.09.04 |
| 申请号 |
US20020297306 |
申请日期 |
2002.12.04 |
| 申请人 |
HOFMANN JOHANN;HEINISCH GOTTFRIED;EASMON JOHNNY;PURSTINGER GERHARD;FIEBIG HEINZ-HERBERT |
发明人 |
HOFMANN JOHANN;HEINISCH GOTTFRIED;EASMON JOHNNY;PURSTINGER GERHARD;FIEBIG HEINZ-HERBERT |
| 分类号 |
A61P35/00;C07D401/12;C07D403/12;C07D413/12;C07D417/12;(IPC1-7):A61K31/506;A61K31/497;A61K31/501;A61K31/470;A61K31/443 |
主分类号 |
A61P35/00 |
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