发明名称 |
Methods and compositions for identification and therapeutic use of genes involved in vascular and proliferative diseases |
摘要 |
The present invention comprises compositions and methods for identification of genes involved in vascular diseases using human endothelial and smooth cell "artery wall" models to capture the cell-cell and cell-matrix communications that are operative in normal and diseases conditions. The present invention further comprises the capture of the complexity of multiple chronic pathologies that coexist in humans by simultaneous treatment of the cells with disease specific stimuli and the identification and use of genes that are regulated by such multiple established disease mediators. The present invention additionally comprises compositions and methods of treatment of vascular disease. |
申请公布号 |
AU2003210769(A1) |
申请公布日期 |
2003.09.02 |
申请号 |
AU20030210769 |
申请日期 |
2003.01.31 |
申请人 |
REDDY US THERAPEUTICS, INC. |
发明人 |
SIVRAM PILLARISETTI;UDAY SAXENA |
分类号 |
C07H21/04;C12Q1/00;C12Q1/68;G01N;G01N33/48;G01N33/50;G06F19/00;(IPC1-7):C12Q1/68 |
主分类号 |
C07H21/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|