NON-AROMATIC 17.ALPHA.-ESTERS OF ANDROSTANE-17.BETA.-CARBOXYLATE ESTERS AS ANTI-INFLAMMATORY AGENTS

摘要

A compound of formula (I); wherein R1 represents represents C1-6 alkyl or C1-6 haloalkyl; R2 represents a 4-7 membered non-aromatic ring containing 1-3 heteroatoms selected from O, N and S optionally substituted with one or more methyl or halogen groups; R3 represents methyl (which may be in either the alpha or beta configuration) or methylene; R4 and R5 are the same or different and each represent hydrogen or halogen; and formula (II) represents a single or a double bond;and salt and solvates thereof.