发明名称 CONTROLLED SYNTHESIS OF ZIPRASIDONE AND COMPOSITIONS THEREOF
摘要 The subject invention provides a ziprasidone composition that comprises not greater than 1000 ppm des-chloro ziprasidone, preferably not greater than about 500 ppm des-chloro ziprasidone, and more preferably not greater than about 100 ppm des-chloro ziprasidone. Methods for synthesizing and using such ziprasidone compositions are also provided.
申请公布号 WO03070246(A1) 申请公布日期 2003.08.28
申请号 WO2003IB00642 申请日期 2003.02.17
申请人 PFIZER PRODUCTS INC. 发明人 BUSCH, FRANK, ROBERT;GROBIN, ADAM, WORTH;HOWARD, HARRY, RALPH, JR.;LEEMAN, KYLE, ROBERT
分类号 C07D417/12;A61K;A61K31/496;A61P;A61P25/00;A61P25/06;A61P25/14;A61P25/22;A61P25/28;A61P27/06;(IPC1-7):A61K31/496 主分类号 C07D417/12
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