| 发明名称 |
CHEMOSENSITIZING WITH LIPOSOMES CONTAINING OLIGONUCLEOTIDES |
| 摘要 |
The invention relates to the use of oliognucleotide containing cationic liposomal formulations to enhance the efficacy of chemotherapy and/or radiotherapy, particularly as a means to chemosensitize cancer are tumor tissues to the efficiencies of chemotherapy. This is particularly advantageo us in the context of treatment of ras expressing tumors such as breast, lung, pancreatic and prostate cancer.
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| 申请公布号 |
CA2476437(A1) |
申请公布日期 |
2003.08.28 |
| 申请号 |
CA20032476437 |
申请日期 |
2003.02.14 |
| 申请人 |
GEORGETOWN UNIVERSITY;NEOPHARM, INC. |
发明人 |
RAHMAN, AQUILUR;DRITSCHILO, ANATOLY;AHMAD, IMRAN;PEI, JIN;MEWANI, RAJSHREE;KASID, USHA;GOKHALE, PRAFULLA |
| 分类号 |
A61K9/127;A61K31/7088;A61K31/7125;A61K31/713;A61K38/00;A61K41/00;A61K45/00;A61K45/06;A61K48/00;A61P35/00;A61P43/00;C07H21/00;C12N15/113;(IPC1-7):A61K9/127 |
主分类号 |
A61K9/127 |
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