INHALATION POWDER CONTAINING THE CGRP ANTAGONIST BIBN4096 AND PROCESS FOR THE PREPARATION THEREOF

摘要

The invention relates to powder inhalation for the treatment of migraines, comprising the CGRP-antagonists 1-[N2~-[3,5-dibrom-N-[[4-(3,4-dihydro-2(1H)- oxochinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4- pyridinyl)-piperazin [BIBN4096] of formula I as an active substance base in the form of spherical nanostructured particles and a method for the producti on thereof.