发明名称 |
Ligands specific for an isoform of the prion protein |
摘要 |
Prion protein, PrP, ligands are provided, especially protease resistant and nuclease resistant ligands. Ligands selective for isoforms such as PrPSC can be prepared. In a related aspect, the PrP ligands are used in diagnostic tests for PrP. The ligands also have potential for a role in the development of therapeutic methods for treatment of TSEs.
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申请公布号 |
US2003162225(A1) |
申请公布日期 |
2003.08.28 |
申请号 |
US20020295798 |
申请日期 |
2002.11.15 |
申请人 |
JAMES WILLIAM SIWARD;HOPE JAMES;TAHIRI-ALAOUI ABDESSAMAD |
发明人 |
JAMES WILLIAM SIWARD;HOPE JAMES;TAHIRI-ALAOUI ABDESSAMAD |
分类号 |
A61K38/00;A61P25/28;C12N15/115;(IPC1-7):G01N33/53;C07K16/18 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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