| 发明名称 |
OXA- AND THIADIAZOLES AND THEIR USE AS METALLOPROTEINASE INHIBITORS |
| 摘要 |
Compounds formula (IA) or (IB), wherein W represents HO(C=O)-, HONH(C=O)- or H(C=O)N(OH)-; X represents -O- or -S-; and R~1, R~2, and R~3 are as defined in the description and claims, are inhibitors of matrix metalloproteinases, in particular MMP9 and/or MMP12. |
| 申请公布号 |
CA2475867(A1) |
申请公布日期 |
2003.08.28 |
| 申请号 |
CA20032475867 |
申请日期 |
2003.02.20 |
| 申请人 |
VERNALIS (OXFORD) LTD.;LABORATOIRES SERONO S.A. |
发明人 |
PAIN, GILLES;GILLON, JEAN-YVES;AYSCOUGH, ANDREW PAUL;DAVIES, STEPHEN JOHN |
| 分类号 |
A61K31/4245;A61P1/00;A61P1/02;A61P1/04;A61P1/16;A61P9/10;A61P11/00;A61P11/06;A61P11/08;A61P13/12;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P19/08;A61P25/00;A61P25/02;A61P27/02;A61P29/00;A61P31/04;A61P35/00;A61P35/04;A61P37/02;A61P37/06;A61P43/00;C07D271/06;C07D285/08;C07D413/04;C07D413/06 |
主分类号 |
A61K31/4245 |
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