| 摘要 |
<P>PROBLEM TO BE SOLVED: To obtain new enediyne compounds each having a highly injurious activity on human caner cells and therefore useful as antitumor agents, and to provide pharmaceuticals containing the same. <P>SOLUTION: The new enediyne compounds are isolated as a result of keenly searching compounds having high antitumor activities from ascidian, a kind of marine organisms. These new compounds are shishijimicin A, B and C. Pharmaceutically acceptable salts thereof are also provided. <P>COPYRIGHT: (C)2003,JPO |
