发明名称 Process for preparing methylene bisphosphonic and salts.
摘要 A process for the preparation of salts of substituted or unsubstituted methylene bisphosphonic acids by hydrolysing the corresponding acid ester with hydrochloric acid, removing water from the acid azeotropically prior to addition of an amine or a base to produce the resultant salt in good yield.
申请公布号 ZA200201661(B) 申请公布日期 2003.08.27
申请号 ZA20020001661 申请日期 2002.02.27
申请人 ASTRAZENECA UK LIMITED 发明人 MARK PURDIE
分类号 C07F9/38 主分类号 C07F9/38
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