| 摘要 |
<P>PROBLEM TO BE SOLVED: To produce a vaccine effective for inhibiting recurrent herpes simplex virus-induced diseases by utilizing a polynucleotide encoding an isolated glycoprotein. <P>SOLUTION: A recombinant herpes simplex virus (HSV) type 1 glycoprotein (gB1) polypeptide which is produced in host cells and is matured peptide, wherein a signal peptide naturally binding thereto is deficient, or a short C-terminal fragment immunologically equivalent to the HSV gB1 polypeptide, is provided. <P>COPYRIGHT: (C)2003,JPO |
