| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a biomaterial having a specified chemical species at least in a surface thereof and provided with a sufficient bone conductivity, and to provide a manufacturing method therefor. <P>SOLUTION: The bone conductive biomaterial is provided with a metal base material and a metal oxide layer formed in a surface of the metal base material. At least a surface of the metal oxide layer has at least one kind of chemical species among PO<SB>4</SB>H<SB>2</SB>, TiOH, ZrOH, NbOH, TaOH and SiOH. As the metal base material, a metal base material containing titanium is desirable, and this base material is heated by a muffle electric furnace to form the metal oxide layer. The base material is dipped with the phosphoric acid buffer, and housed in a pressure resistant container, and treated with water and heat at 100°C or more of temperature and at 0.1 MPa or more of pressure to generate the specified chemical species at least in the surface of the metal oxide layer to contain it. Thickness of the metal oxide layer is for example, at 5 μm. <P>COPYRIGHT: (C)2003,JPO |
