| 摘要 |
PROBLEM TO BE SOLVED: To provide a model animal with liver function failure, having failure in repair function of failure in glomerulus. SOLUTION: The method for producing the model animal with the liver function failure, having the failure in the repair function in the glomerulus involves a step for damaging the glomerulus of an animal having enhanced expression of a megsin gene in the glomerulus. The model animal with the liver function failure is new. The model animal is useful for the research of the repair mechanism of the glomerulus and the screening of a therapeutic agent of human renal dysfunction. COPYRIGHT: (C)2003,JPO
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