PROCESS FOR PREPARING CINNAMIC ACID DERIVATIVES

摘要

PURPOSE: A process for preparing cinnamic acid derivatives is provided, thereby preparing cinnamic acid derivatives in higher yield. CONSTITUTION: A process for preparing cinnamic acid derivatives of the formula 1 comprises the steps of: reacting bromobenzene derivatives with acrylate derivatives in the presence of keben palladium complex of the formula 4 and base, wherein R is hydrogen, lower alkyl such as methyl or ethyl, or acid salt such as H·HCl; the bromobenzene derivative is 4-(1-imidazolylmethyl)-4'-bromobenzene of the formula 2; the acrylate derivative is a compound of the formula 3; the keben palladium complex of the formula 4 is di-1,3-dimethylimidazolium palladium diiodide complex; and R1 is lower alkyl such as methyl or ethyl.