发明名称 |
Methods and reagents for peptide-BIR interaction screens |
摘要 |
The invention features a substantially pure polypeptide having a length of less than 100 amino acids and capable of forming a complex with a polypeptide that includes a BIR domain. The invention also features displacement assays in which the ability of a candidate compound to disrupt the interaction between a BIR domain-containing polypeptide and a polypeptide of the invention is indicative of the ability of the candidate compound to modulate IAP biological activity.
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申请公布号 |
US2003157522(A1) |
申请公布日期 |
2003.08.21 |
申请号 |
US20020293371 |
申请日期 |
2002.11.12 |
申请人 |
BOUDREAULT ALAIN;KORNELUK ROBERT G.;LACASSE ERIC;LISTON PETER |
发明人 |
BOUDREAULT ALAIN;KORNELUK ROBERT G.;LACASSE ERIC;LISTON PETER |
分类号 |
A61K38/00;C07K1/04;C07K1/06;C07K5/103;C07K7/06;(IPC1-7):C12Q1/68;G01N33/53;C07H21/04;C12P21/02;C12N5/06;C07K14/47 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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