| 摘要 |
<p>Inositol phosphate esters and conjugates formed between the compounds and a coupling partner are disclosed, in particular compounds based on a myo-inositol which is substituted at position 1 with a phosphate ester group, at position 2 with a sugar group and at position 4 and/or position 6 with an amino acid group. The compounds are based on the structure of phosphatidylinositol hexamannosides (PIM6) of Mycobacteria and may be used as mimics of the naturally occurring PIMs in order to induce biological responses normally attributed to the natural compound or may be used as biologically inert carriers in order to deliver specific pharmaceutically active compounds to lipid rafts/caveolae.</p> |
