发明名称 |
METHODS OF INHIBITING HIV-1 VPR ACTIVITY AND HIV-1 INFECTIVITY USING ATR OR RAD17 INHIBITORS |
摘要 |
Methods are disclosed for inhibiting the activity of a viral protein R (Vpr), inhibiting HIV replication, and treating or preventing an HIV infection through the use of an inhibitor of ATR or Rad17. Newly discovered ATR or Rad17 inhibitors are disclosed for use in accordance with the present invention, as are previously known compounds based upon their newly discovered property as inhibitors of ATR or Rad 17.
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申请公布号 |
CA2475768(A1) |
申请公布日期 |
2003.08.21 |
申请号 |
CA20032475768 |
申请日期 |
2003.02.13 |
申请人 |
UNIVERSITY OF ROCHESTER;UNIVERSITY OF UTAH |
发明人 |
PLANELLES, VICENTE;ROSHAL, MIKHAIL;ZHU, YONG HONG |
分类号 |
A61K31/00;A61K31/5377;A61K31/553;A61K31/704;A61K41/00;A61K45/06;C12N15/113;(IPC1-7):C07H21/04;C07H21/02;C12N5/10;A61P31/18;A61K31/537;A61K31/708;A61K31/710;C12N15/85 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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