发明名称 |
METHOD AND DEVICE FOR DETECTING BACTERIAL CONTAMINATION |
摘要 |
A device and method for detecting the presence or absence of a prokaryotic microorganism are provided, comprising the steps of identifying a protein, such as a microbial-specific protease that characterizes the presence of a specific prokaryotic microbe and thereby provides a marker for that microbe; detecting the protease that is a marker for the presence of a specific prokaryotic microbe by cleaving a substance when the protease is present; and signaling the presence of that protease when cleavage has occurred. More specifically, the method comprises identifying at least one outer membrane protein or a secreted protein that is unique to a particular microbial pathogen such as for example Listeria monocytogenes and that is substrate specific. |
申请公布号 |
WO0210433(A3) |
申请公布日期 |
2003.08.21 |
申请号 |
WO2001US14613 |
申请日期 |
2001.05.03 |
申请人 |
EXPRESSIVE CONSTRUCTS, INC. |
发明人 |
SANDERS, MITCHELL, C. |
分类号 |
G01N33/544;C12M1/34;C12N15/09;C12Q1/04;C12Q1/24;C12Q1/37;G01N21/77;G01N21/78;G01N33/02;G01N33/569 |
主分类号 |
G01N33/544 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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