METHODS AND COMPOSITION FOR MODULATING TYPE I MUSCLE FORMATION USING PGC-1.ALPHA.-

摘要

The invention provides novel methods and compositions for modulating type I muscle formation through modulation of PGC-1.alpha. activity or expression. Also provided are methods for identifying compounds that modulate type I muscle formation through modulation of PGC-1.alpha. activity or expression. Further provided are methods for treating disorders associated with type I and/or type II muscle formation, as well as transgenic animals expressing PG C- 1.alpha. in muscle.