发明名称 INHIBITION OF LUNG METASTASES BY AEROSOL DELIVERY OF P53 GENE AND ANTI-CANCER COMPOUNDS
摘要 <p>The present invention provides a method of inhibiting growth of lung metastases in an individual comprising the steps of administering in a combination an aerosolized polyethylenimine-DNA complex and an aerosolized liposome-anticancer drug complex with both of the complexes delivered via aerosolization. Delivery of both the DNA and the anticancer drug via this method inhibits growth of lung metastases in the individual. Also provided is a method of inhibiting growth of lung metastases in an individual by the administration in combination via aerosolization of a polyethylenimine-p53 complex and a dilauroylphosphatidylcholine-9-nitrocamptothecin complex.</p>
申请公布号 WO2003068936(P1) 申请公布日期 2003.08.21
申请号 US2003004522 申请日期 2003.02.14
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