| 发明名称 |
TAOJIKs as modifiers of the beta-catenin pathway and methods of use |
| 摘要 |
Human TAOJIK genes are identified as modulators of the beta-catenin pathway, and thus are therapeutic targets for disorders associated with defective beta-catenin function. Methods for identifying modulators of beta-catenin, comprising screening for agents that modulate the activity of TAOJIK are provided.
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| 申请公布号 |
US2003157531(A1) |
申请公布日期 |
2003.08.21 |
| 申请号 |
US20020317835 |
申请日期 |
2002.12.12 |
| 申请人 |
COSTA MICHAEL A.;GENDREAU STEVEN BRIAN;DORA EMERY G.;NICOLL MONIQUE;URBANI LENORE;LARSON JEFFREY S. |
发明人 |
COSTA MICHAEL A.;GENDREAU STEVEN BRIAN;DORA EMERY G.;NICOLL MONIQUE;URBANI LENORE;LARSON JEFFREY S. |
| 分类号 |
A61K45/00;A61P9/00;A61P35/00;A61P43/00;C12N15/09;C12Q1/02;C12Q1/48;C12Q1/68;G01N33/15;G01N33/50;G01N33/574;(IPC1-7):C12Q1/68 |
主分类号 |
A61K45/00 |
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