发明名称 |
MUTATED GENE CODING FOR A LAT PROTEIN AND THE BIOLOGICAL APPLICATIONS THEREOF |
摘要 |
The present invention relates to a mutated gene coding for a mutant LAT protein leading to an exaggerated TH2 differentiation. The invention relates to biological structures containing said mutant, particularly, non-human LAT gene mutated animals, plasmids, chromosomal DNA~s, embryos comprising said mutated gene, and applications thereof. The invention further relates to screening method for drug useful for treatment against asthma and allergy. Otherwise, the invention relates to method for producing IgE antibodies.</SD OAB> |
申请公布号 |
CA2474885(A1) |
申请公布日期 |
2003.08.21 |
申请号 |
CA20032474885 |
申请日期 |
2003.02.14 |
申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE |
发明人 |
AGUADO VIDAL, ENRIQUE;MALISSEN, BERNARD;MALISSEN, MARIE |
分类号 |
A01K67/027;A61K38/00;A61K45/00;A61P11/06;A61P37/08;A61P43/00;C07K14/47;C07K16/00;C07K16/18;C12M1/00;C12M1/40;C12N5/10;C12N15/09;C12N15/12;C12N15/63;C12P21/08;C12Q1/68;G01N33/15;G01N33/50;G01N33/68 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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