METHODS AND COMPOSITION FOR MODULATING TYPE I MUSCLE FORMATION USING PGC-1alpha-

摘要

The invention provides novel methods and compositions for modulating type I muscle formation through modulation of PGC-1alpha activity or expression. Also provided are methods for identifying compounds that modulate type I muscle formation through modulation of PGC-1alpha activity or expression. Further provided are methods for treating disorders associated with type I and/or type II muscle formation, as well as transgenic animals expressing PGC-1alpha in muscle.