CELLS TO BE USED IN PRODUCING VIRUS VECTOR, PROCESS FOR PRODUCING THE SAME AND PROCESS FOR PRODUCING VIRUS VECTOR WITH THE USE OF THE CELLS

摘要

It is intended to establish a novel cell line for efficiently producing a virus vector without resort to any troublesome operations and provide a process for producing a virus vector having a high titer with the use of the cell line. Namely, cells to be used in producing a virus vector having an antisense gene been transferred thereinto are provided, wherein the gene expresses an antisense RNA against the whole or partial sequence of a sense RNA expressed by a gene encoding a cytotoxic polypeptide. <IMAGE>