| 摘要 |
A method for preparing a resinate comprises blending an active substance with a resin and a solvent to form an active substance/resin/solvent mixture and then maintaining said mixture at a temperature and pressure such that it maintains a liquid state for 1 second to 48 hours. The active substance may be either water soluble, such as nicotine, or poorly water soluble, such as ondomethacin, nalfinavir or midazolam. The solvent may be water immiscible or may be a C1 to C4 fluorinated hydrocarbon such as tetrafluoroethane. The active substance may be loaded at 100% of the exchange capacity of the resin. |
