Fenylalaninenamid-derivater som har en cyklobutengruppe, for anvendelse somintegrin-inhibitorer

摘要

Phenylalanine enamide derivatives of formula (1) are described:
wherein R 1 , R x , R y , R z , X and V are as defined in claim 1.
The compounds are able to inhibit the binding of integrins to their ligands and are of use in the prophylaxis and treatment of immuno or inflammatory disorders or disorders involving the inappropriate growth or migration of cells.