发明名称 |
Fluorescence-labeled probe for DNA and a fluorescence-labeled plasmid |
摘要 |
This invention provides a precursor compound of a novel fluorescence-labeled probe for DNA, prepared by covalent binding of a fluorescent substance such as fluorescein isothiocyanate, wherein a conjugating group was bounded, with aminoalkylate phenylamine. This invention also provides a novel fluorescence-labeled probe for DNA by diazotizing amino group of phenylamine contained in the precursor compound. Furthermore, a fluorescence labeled plasmid can be produced by conjugating the fluorescence-labeled probe and purine ring of guanine contained in the DNA plasmid through diazonium group.
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申请公布号 |
US6608213(B1) |
申请公布日期 |
2003.08.19 |
申请号 |
US20010814218 |
申请日期 |
2001.03.22 |
申请人 |
TOKYO INSTITUTE OF TECHNOLOGY |
发明人 |
SATO TOSHINORI;OKAHATA YOSHIO |
分类号 |
G01N33/533;C07D311/82;C07H19/16;C07H21/00;C12N15/09;C12N15/65;C12Q1/68;G01N21/78;G01N33/53;G01N33/58;(IPC1-7):C07D311/78;C07D311/88;C07D317/08;C07H21/02;C07H21/04 |
主分类号 |
G01N33/533 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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