发明名称 NUCLEAR MAGNETIC RESONANCE IMAGING AGENT
摘要 A nuclear magnetic resonance imaging agent comprises a complex compound composed of (a) dialdehyde-saccharide having a molecular weight of from 500 to 10,000, at least one of constituent monosaccharides of which is oxidation-cleaved, (b) at least one complexing agent that is chemically coupled to an aldehyde group of the dialdehyde-saccharide and (c) a paramagnetic metal ion that is chemically coupled to the complexing agent. The agent has improved performance, included a more desirable retention time in blood.
申请公布号 CA2073482(C) 申请公布日期 2003.08.19
申请号 CA19922073482 申请日期 1992.07.08
申请人 NIHON MEDI-PHYSICS CO., LTD. 发明人 HASHIGUCHI, YUJI;IWAI, KUMIKO;SERI, SHIGEMI;KONDO, SUSUMU;AZUMA, MAKOTO
分类号 A61K49/00;A61K49/08;A61K49/12;C07H15/04;C08B33/08;C08B37/00;(IPC1-7):A61K49/00 主分类号 A61K49/00
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