发明名称 4-quinolinemethanol derivatives as purine receptor antagonists (II)
摘要 Use of a compound of formula (I) as defined herein, or a pharmaceutically acceptable salt or prodrug thereof, in the manufacture of a medicament for the treatment or prevention of a disorder in which the blocking of purine receptors, particularly adenosine receptors and more particularly A2a receptors, may be beneficial, such as a movement disorder, for example, Parkinson's Disease or progressive supemuclear palsy, Huntingtons disease, multiple system atrophy, corticobasal degeneration, Wilsons disease, Hallerrorder-Spatz disease, progressive pallidal atrophy, Dopa-responsive dystonia-Parkinsonism, spasticity, Alzheimer's disease or other disorders of the basal ganglia which result in dyskinesias.
申请公布号 US6608085(B1) 申请公布日期 2003.08.19
申请号 US20010786472 申请日期 2001.05.09
申请人 VERNALIS RESEARCH LIMITED 发明人 GILLESPIE ROGER JOHN;LERPINIERE JOANNE;GILES PAUL RICHARD;ADAMS DAVID REGINALD;KNUTSEN LARS JACOB STRAY;CLIFFE IAN ANTHONY
分类号 A61K31/47;A61P25/16;A61P25/24;(IPC1-7):A61K31/470;A61K31/537 主分类号 A61K31/47
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