发明名称 SPIROIMIDAZOLINDERIVATE UND IHRE VERWENDUNG ALS ALPHA2-ADRENOREZEPTOR-ANTAGONISTEN UND MONOAMINO- WIEDERAUFNAHME-BLOCKER
摘要 Spiro(imidazoline-anthracene) derivatives (I) are new. Spiro(imidazoline-anthracene) derivatives of formula (I) and their base or acid addition salts are new. R1-R4 = H, 1-6C alkyl, 1-6C alkoxy, OH, 1-6C polyhalogenoalkyl, cyano, nitro, amino, 1-6C alkylamino, di (1-6C) alkylamino, 1-6C thioalkyl, 1-6C sulfonylalkyl, 1-6C sulfinylalkyl, carboxy, 1-6C alkoxycarbonyl, 1-6C alkylcarbonyloxy, formyl, carbamoyl, carboxamide, phenyl, benzyl or halo; B' = a group of formula (i) or (ii); R = H, 1-6C alkyl or benzyl. Independent claims are also included for: (1) the preparation of (I); and (2) pharmaceutical compositions comprising at least one compound (I).
申请公布号 AT246680(T) 申请公布日期 2003.08.15
申请号 AT19990403189T 申请日期 1999.12.17
申请人 LES LABORATOIRES SERVIER 发明人 CORDI, ALEX;MILLAN, MARK;NEWMAN-TANCREDI, ADRIAN;BROCCO, MAURICETTE
分类号 A61K31/4184;A61P3/04;A61P15/10;A61P25/00;A61P25/16;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P43/00;C07D235/02 主分类号 A61K31/4184
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