ANTISENSE MODULATION OF SPHINGOSINE-1-PHOSPHATE LYASE EXPRESSION

摘要

Antisense compounds, compositions and methods are provided for modulating the expression of sphingosine-l-phosphate lyase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding sphingosine-l-phosphate lyase. Methods of using these compounds for modulation of sphingosine-1-phosphate lyase expression and for treatment of diseases associated with expression of sphingosine-l-phosphate lyase are provided.