SYNTHESIS OF INOSITOLPHOSPHATE GLYCAN MOLECULES: TREATMENT OF CELL PROLIFERATION DISORDERS AND METABOLIC DISORDERS CHARACTERIZED BY INSULIN RESISTANCE

摘要

The invention concerns a compound of formula A wherein: R1 is selected from the group consisting of OH, an oligosaccharide, a polysaccharide, and R2=R3=OH; or at least one of the groups R1, R2, R3 is a group capable of modifying the lipophilicity of the compound A, the other or the other two of the three groups being OH; and R4 is selected from the group consisting of OH, NH2 and a group capable of modifying the lipophilicity of the compound A; and R6 is H or CH2OH; and X is selected among O, NH, S, CH2; and R5 is selected among OH, an oligosaccharide, a polysaccharide and a group capable of modifying the bioavailability of the compound A, and its pharmaceutically acceptable salts.