摘要 |
<p>Piperidine derivatives represented by the following general formula (I) (wherein each symbol is as defined in the description) and production intermediates thereof: (I) Because of having a phosphodiesterase 4 inhibitory activity, the compounds represented by the general formula (I) are useful in preventing and/or treating inflammatory diseases, diabetic diseases, allergic diseases, autoimmune diseases, eye diseases, osteoporosis, bone fracture, arthritis deformans, obesity, overeating, depression, Parkinson’s disease, dementia, ischemic reperfusion injury, leukemia, acquired immunodeficiency syndrome (AIDS), shock, systemic inflammatory response syndrome (SIRS), etc.</p> |