PROCESS FOR THE PRODUCTION OF L-AMINO ACIDS USING CORYNEFORM BACTERIA

摘要

The invention relates to a process for the production of L-amino acids, in which the following steps are carried out: a) fermentation of the coryneform bacteria producing the desired L-amino acid, in which at least the gene coding for S-adenosylmethionine synthetase and/or the gene coding for a transporter for branched-chain amino acids is/are attenuated, b) enrichment of the desired L-amino acid in the medium or in the bacterial cells, and c) isolation of the L-amino acid, and optionally bacteria are used in which in addition further genes of the biosynthesis pathway of the desired L-amino acid are enhanced, or bacteria are used in which the metabolic pathways that reduce the formation of the desired L-amino acid are at least partially switched off.