发明名称 |
Substituted (aminoiminomethyl or aminomethyl) benzoheteroaryl compounds |
摘要 |
This invention is directed to an (aminoiminomethyl or aminomethyl)benzoheteroaryl compound of formula I which is useful for inhibiting the activity of Factor Xa by combining said compound with a composition containing Factor Xa. The present invention is also directed to compositions containing compounds of the formula I, methods for their preparation, their use, such as in inhibiting the formation of thrombin or for treating a patient suffering from, or subject to, a disease state associated with a physiologically detrimental excess amount of thrombin.
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申请公布号 |
US2003153604(A1) |
申请公布日期 |
2003.08.14 |
申请号 |
US20030372499 |
申请日期 |
2003.02.24 |
申请人 |
AVENTIS PHARMACEUTICALS INC. |
发明人 |
DANKULICH WILLIAM P.;MCGARRY DANIEL G.;BURNS CHRISTOPHER;GALLAGHER TIMOTHY F.;VOLZ FRANCIS A. |
分类号 |
A61K31/4045;A61K31/4178;A61K31/433;A61K31/4355;A61K31/437;A61K31/4439;A61K31/454;A61K31/455;A61K31/496;A61K31/501;A61K31/5025;A61K31/506;A61K31/5377;A61P7/02;A61P9/10;A61P31/04;A61P31/12;A61P35/00;A61P41/00;A61P43/00;C07D209/42;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D409/12;C07D409/14;C07D413/12;C07D417/12;C07D471/04;C07D487/04;C07D491/04;C07D491/048;C07D521/00;(IPC1-7):C07D409/02;C0745/02;C07D333/72;A61K31/443;A61K31/405;A61K31/402;A61K31/381;A61K31/343 |
主分类号 |
A61K31/4045 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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