This invention relates the identification of a novel co-factor (termed 'Aha1') that interacts with the molecular chaperone Heat shock protein 90 (Hsp90) and stimulates Hsp90 activity. Various assay methods and therapeutic applications based on this interaction are provided.
申请公布号
WO03067262(A2)
申请公布日期
2003.08.14
申请号
WO2003GB00492
申请日期
2003.02.04
申请人
CANCER RESEARCH TECHNOLOGY LIMITED;WORKMAN, PAUL;AHERNE, WYNNE;PEARL, LAURENCE;PRODROMOU, CHRISOSTOMOS